To prevent the spread of COVID-19, influenza, and RSV, there are several actions you can take. Firstly, it is recommended that you get vaccinated as soon as possible, as this is the most effective way to prevent these infections. Secondly, it is important to practice good hygiene by washing your hands frequently, covering your mouth and nose when you cough or sneeze, and using hand sanitizer when soap and water are not available. Additionally, wearing a mask in public places can help prevent the spread of the virus. If you are sick, it is important to stay home to avoid spreading the virus to others. Finally, keeping your environment clean by disinfecting frequently touched surfaces can also help prevent the spread of COVID-19, flu, and RSV.
The protocol has two phases: pre-exposure (long-term) and post-exposure (short-term) to prevent infections. The pre-exposure phase involves vaccination, good hygiene practices, and avoiding close contact with sick people. The post-exposure phase involves taking antiviral medication, quarantining, or isolating oneself. The protocol provides comprehensive guidance on infection prevention and what to do in case of exposure or infection, helping individuals reduce their risk of contracting and spreading infections.
If you have flu-like symptoms, please consult My Care Labs: Early COVID Testing, or: RSV and Flu Test Protocols.
Regarding This Protocol
- Learn how nutritional therapeutics can help with COVID-19.
- Learn about the safety of vitamins and nutraceuticals during pregnancy.
- Look for directory of providers and pharmacies.
How to Avoid Infection Before Being Exposed
To prevent infection, it is recommended to gargle with antiseptic and antimicrobial mouthwash twice daily, making sure not to swallow it. Mouthwashes containing chlorhexidine, povidone-iodine, cetylpyridinium chloride, or eucalyptus, menthol, and thymol are good options. Vitamin D is also important, with an optimal target of greater than 50 ng/ml. Table 1 presents a safe and practical treatment schedule for raising serum concentrations in non-urgent situations, while Table 2 should be used when recent serum concentration levels are unavailable. Additionally, taking 500 mg of vitamin C twice daily, 20-50 mg/day of zinc, and 1-6 mg of melatonin (slow/extended) nightly can help prevent infection. However, patients should be aware that melatonin may cause drowsiness and vivid dreams in some cases.
- Elderberry syrup, supplements, or gummies: can be taken during times of high COVID-19, influenza, and RSV transmission, following the manufacturer’s dosing recommendations. A triple combination of elderberry, vitamin C, and zinc can be a convenient approach. However, patients with autoimmune disease should be cautious and take no more than two weeks off, closely monitoring their symptoms.
- Resveratrol Alone or in Combination Flavonoid supplement: Taking a daily supplement of 400-500 mg of Resveratrol alone or in combination with flavonoids is recommended. However, pregnant women should avoid resveratrol, quercetin, and pterostilbene as their safety has not been established. Quercetin and ivermectin should not be taken together due to the possibility of drug interaction. Chronic weekly or twice-weekly ivermectin prophylaxis is no longer recommended for most people, but it can be considered in those with significant comorbidity or a lack of natural immunity. Daily ivermectin can be taken before and during periods of high potential exposure, and when the first symptoms of a viral syndrome appear, ivermectin at treatment doses should be taken right away.
Table 1: Recommendations for Upfront Loading Dose Regimens to Replace Vitamin D Stores in the Body
This table shows the recommended doses of oral vitamin D for non-obese adults weighing 70 kg to maintain serum 25(OH)D concentrations above 50 ng/mL (125 nmol/L) when serum vitamin D levels are available. It includes the initial bolus dose, weekly dose, frequency, and duration of administration in non-emergency situations.
|Baseline Vitamin D (ng/mL)**||Vitamin D dose, 50,000 IU capsules: Initial and weekly $||Duration (Number of Weeks)||Total Amount Needed to Correct Vit. D, Deficiency (IU, in Millions)#|
|Initial Bolus Dose (IU)||Follow-Up: $$ The Number of 50,000 IU Caps/Week|
|< 10||300,000||x 3||8 to 10||1.5 to 1.8|
|11-15||200,000||x 2||8 to 10||1.0 to 1.2|
|16-20||200,000||x 2||6 to 8||0.8 to 1.0|
|21-30||100,000||x 2||4 to 6||0.5 to 0.7|
|31-40||100,000||x 2||2 to 4||0.3 to 0.5|
|41-50||100,000||x 1||2 to 4||0.2 to 0.3|
After completing the loading-dose schedule, an appropriate daily or weekly maintenance dose should be taken. The dose may need to be adjusted for those who are underweight or overweight. To convert ng/mL to nmol/L, multiply the amount in ng by 2.5. One µg is equal to 40 IU. The recommended replacement doses can be taken as single or cumulative doses, two to three times a week, spread out over a few weeks, starting from week two. The estimated total vitamin D dose required to replenish the body stores (i.e., the deficit) is provided in the last column.
Table 2. Vitamin D Dosing in the Absence of a Baseline Vitamin D Level
Longer-term maintenance schedules of oral vitamin D based on body weight to maintain the levels above 50 ng/mL (125 nmol/L) when the serum 25(OH)D concentrations are unknown.
|Bodyweight Category||Dose kg/day (IU)||Dose (IU) (Daily or Weekly)*|
|(Age) or Using BMI (for age > 18) (kg/Ht. M2)||Average Body Weight (Kg)||Daily dose (IU)||Once a week (IU)|
|BMI ≤ 19||50-60 (under-weight adult)||60 to 80||3500-5000||25,000-35,000|
|BMI < 29||70-90 (normal; non-obese)||70 to 90||5000-8000||35,000-50,000|
|BMI 30-39||90-120 (obese persons)#||90 to 130||8000-15,000||50,000-100,000|
|BMI ≥ 40$||140 (morbidly obese)$||140 to 180||18,000-30,000||125,000-200,000|
This table provides an example of a daily or once-a-week dose range for adults based on their body type, with appropriate dose reductions necessary for children. For those with chronic comorbid conditions such as hypertension, diabetes, asthma, COPD, CKD, depression, and osteoporosis, higher doses of vitamin D are needed to reduce all-cause mortality. The doses recommended for people with obesity (BMI, 30–39) can be used for them. Individuals suffering from multiple sclerosis, cancer, migraine headaches, or psoriasis, or those taking medications that significantly increase vitamin D metabolism, such as anti-epileptic and anti-retroviral agents, should consider taking age-appropriate doses recommended for those suffering from morbid obesity (BMI 40), which are at the higher end of the daily doses in the fourth row.
How to Avoid Infection If You’ve Been Exposed
- It is highly recommended to use a combination of nasal antiseptic sprays and oropharyngeal mouthwashes for Naso-Oropharyngeal Hygiene. Use a nasal spray that contains 1% povidone-iodine, such as Immune MistTM, CofixRXTM, or IonovoTM, 2-3 times daily. For the mouthwash, choose one that contains chlorhexidine, povidone-iodine, cetylpyridinium chloride, such as ScopeTM, CrestTM, or ActTM, or a combination of eucalyptus, menthol, and thymol, such as ListerineTM.
- Elderberry: Follow the manufacturer’s instructions to take gummy, supplement, or syrup containing 500-1000 mg vitamin C, four times a day for one week. Take 50-90 mg of Elemental Zinc daily for one week. For Melatonin (slow/extended release), take 2-5 mg at night.
- Resveratrol/Combination Flavonoid supplement: It is recommended to take a combination of flavonoids containing resveratrol, quercetin, and pterostilbene, 500 mg twice daily.
- Source: https://covid19criticalcare.com/treatment-protocols/i-prevent-protect/